Kugel, Sita: search on Z-Library

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1

The human proton-coupled folate transporter

Desmoulin, Sita Kugel, Hou, Zhanjun, Gangjee, Aleem, Matherly, Larry H.

Journal:

Cancer Biology & Therapy

Year:

2012

Language:

english

File:

PDF, 1.98 MB

english, 2012

2

Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3- d ]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate Transporter and Folate Receptor Selectivity over the Reduced Folate Carrier That Inhibits β-Glycinamide Ribonucleotide Formyltransferase

Wang, Lei, Desmoulin, Sita Kugel, Cherian, Christina, Polin, Lisa, White, Kathryn, Kushner, Juiwanna, Fulterer, Andreas, Chang, Min-Hwang, Mitchell-Ryan, Shermaine, Stout, Mark, Romero, Michael F., Ho

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.68 MB

english, 2011

3

Synthesis and Biological Activity of 6-Substituted Pyrrolo[2,3- d ]pyrimidine Thienoyl Regioisomers as Inhibitors of de Novo Purine Biosynthesis with Selectivity for Cellular Uptake by High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier

Wang, Lei, Cherian, Christina, Kugel Desmoulin, Sita, Mitchell-Ryan, Shermaine, Hou, Zhanjun, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

4

The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine

Etchegaray, Jean-Pierre, Chavez, Lukas, Huang, Yun, Ross, Kenneth N., Choi, Jiho, Martinez-Pastor, Barbara, Walsh, Ryan M., Sommer, Cesar A., Lienhard, Matthias, Gladden, Adrianne, Kugel, Sita, Silber

Journal:

Nature Cell Biology

Year:

2015

Language:

english

File:

PDF, 7.13 MB

english, 2015

5

SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b

Kugel, Sita, Sebastián, Carlos, Fitamant, Julien, Ross, Kenneth N., Saha, Supriya K., Jain, Esha, Gladden, Adrianne, Arora, Kshitij S., Kato, Yasutaka, Rivera, Miguel N., Ramaswamy, Sridhar, Sadreyev,

Journal:

Year:

2016

Language:

english

File:

PDF, 5.19 MB

english, 2016

6

Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3- d ]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors over the Reduced Folate Carrier and Proton-Coupled Folate Transporter for Cellular Entry †

Deng, Yijun, Zhou, Xilin, Kugel Desmoulin, Sita, Wu, Jianmei, Cherian, Christina, Hou, Zhanjun, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 313 KB

english, 2009

7

Synthesis and Antitumor Activity of a Novel Series of 6-Substituted Pyrrolo[2,3- d ]pyrimidine Thienoyl Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors and the Proton-Coupled Folate Transporter over the Reduced Folate Carrier for Cellular Entry

Wang, Lei, Cherian, Christina, Kugel Desmoulin, Sita, Polin, Lisa, Deng, Yijun, Wu, Jianmei, Hou, Zhanjun, White, Kathryn, Kushner, Juiwanna, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

8

Chromatin and beyond: the multitasking roles for SIRT6

Kugel, Sita, Mostoslavsky, Raul

Journal:

Trends in Biochemical Sciences

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

9

Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter

Christina Cherian, Sita Kugel Desmoulin, Lei Wang…

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 497 KB

english, 2013

10

Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer

Kugel, Sita, Feldman, Jessica L., Klein, Mark A., Silberman, Dafne M., Sebastián, Carlos, Mermel, Craig, Dobersch, Stephanie, Clark, Abbe R., Getz, Gad, Denu, John M., Mostoslavsky, Raul

Journal:

Year:

2015

Language:

english

File:

PDF, 3.86 MB

english, 2015

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